General information
Organisation
The French Alternative Energies and Atomic Energy Commission (CEA) is a key player in research, development and innovation in four main areas :
• defence and security,
• nuclear energy (fission and fusion),
• technological research for industry,
• fundamental research in the physical sciences and life sciences.
Drawing on its widely acknowledged expertise, and thanks to its 16000 technicians, engineers, researchers and staff, the CEA actively participates in collaborative projects with a large number of academic and industrial partners.
The CEA is established in ten centers spread throughout France
Reference
SL-DRF-25-0933
Direction
DRF
Thesis topic details
Category
Life Sciences
Thesis topics
Lanthanide complexes acting as supramolecular glue to induce protein crystallization
Contract
Thèse
Job description
The primary objective of the project is to understand how dedicated lanthanide complexes induce protein crystallization and exploit them in new field of macromolecular crystallography. During the PhD project, we aim to (1) Explore the properties of the new molecules; (2) To develop a predictive tool on the propensity of the molecules to induce crystallization; (3) To develop the detection of sub-micron size crystals; (4) To study the possibility to generate crystals directly in cells.
University / doctoral school
Ecole Doctorale de Physique de Grenoble (EdPHYS)
Université Grenoble Alpes
Thesis topic location
Site
Grenoble
Requester
Position start date
01/10/2025
Person to be contacted by the applicant
GIRARD Eric 
eric.girard@ibs.fr
CEA
DRF/IRIG//IBS
Institut de Biologie Structurale
Groupe Extremophiles et grands
assemblages moléculaires
Campus EPN CS10090
71 Avenue des Martyrs
38044 GRENOBLE cedex 9
0457428645
Tutor / Responsible thesis director
GIRARD Eric eric.girard@ibs.fr
CEA
DRF/IRIG//IBS
Institut de Biologie Structurale
Groupe Extremophiles et grands
assemblages moléculaires
Campus EPN CS10090
71 Avenue des Martyrs
38044 GRENOBLE cedex 9
0457428645
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