Air represents a complex contamination pathway that is difficult to control and through which numerous biological, biochemical, or chemical agents can affect populations and healthcare workers. Standard detection approaches, whether qPCR, antigen tests, or ELISA tests, rely on reagents specific to known and targeted agents. These approaches are therefore unsuitable for detecting an unknown pathogen that could result in a new pandemic. To face such unknown agents, new biosensors will be needed to distinguish between pathogenic and non-pathogenic agents. Also, these sensors will have to be miniature for deployment.

With a new microfluidic system the present project aims to explore original approaches for conducting such detection without preconceived notions. Based on the laboratory's experience and developments, the PhD will include :
- developing new materials and designs to optimize and to enable multiple bioaerosol sampling;
- developing a biomimetic biochip and optimize molecular interactions using microflows controlled at the micro/milliscale.

You will design a microfluidic card integrating new detection strategies and study them experimentally using prototypes already developed in the laboratory.