General information
Organisation
The French Alternative Energies and Atomic Energy Commission (CEA) is a key player in research, development and innovation in four main areas :
• defence and security,
• nuclear energy (fission and fusion),
• technological research for industry,
• fundamental research in the physical sciences and life sciences.
Drawing on its widely acknowledged expertise, and thanks to its 16000 technicians, engineers, researchers and staff, the CEA actively participates in collaborative projects with a large number of academic and industrial partners.
The CEA is established in ten centers spread throughout France
Reference
SL-DRF-24-0516
Direction
DRF
Thesis topic details
Category
Life Sciences
Thesis topics
The role of the signaling nucleotide ppGpp in plant resilience to climate change.
Contract
Thèse
Job description
Amidst the growing challenges of climate change, crops face threats from rising temperatures and prolonged droughts, leading to reduced photosynthetic efficiency and the need for rapid stress acclimation. In this PhD project we will investigate the role of the nucleotide guanosine tetraphosphate (ppGpp) signalling pathway, a known regulator of plastid function and photosynthesis. Recent preliminary work from our and other labs indicate that ppGpp plays a pivotal role in plant stress acclimation, and we have indications that perturbation of ppGpp signalling affects plant responses to heat stress. This research aims to explore how ppGpp is involved in plant acclimation to heat and drought stress. Using a combination of physiological evaluations, biochemical techniques, transcriptomics, and biosensors this study will investigate the modulation of ppGpp levels under stress conditions, its impact on plastid genome expression, and its intersection with other signalling pathways. The ultimate goal is to enhance our understanding of ppGpp's role in plant acclimation, offering insights for improving crop resilience in a climate-challenged world.
University / doctoral school
Sciences de la Vie et de la Santé (SVS)
Aix-Marseille Université
Thesis topic location
Site
Cadarache
Requester
Position start date
01/10/2024
Person to be contacted by the applicant
JAVOT Hélène helene.javot@cea.fr
CEA
DRF/BIAM/SBVME/LGBP
CEA, Cadarache
UMR 7265,
13108 St Paul Lez Durance
33 (0)4 42 25 78 16
Tutor / Responsible thesis director
FIELD BENJAMIN ben.field@univ-amu.fr
CNRS
IBEB/SBVME/LGBP
CEA/BIAM/LGBP
Institut de Biosciences et biotechnologies d'Aix-Marseille,
Faculté des Sciences de Luminy,
163 Avenue de Luminy ,
13009 Marseille
+33 491 829 562
En savoir plus
https://www.cite-des-energies.fr/chercheur/ben-field/
https://www.cite-des-energies.fr/biam/recherche/lgbp/equipe-et-competences-lgbp/