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Nano-object simulations in biological media


Thesis topic details

General information

Organisation

The French Alternative Energies and Atomic Energy Commission (CEA) is a key player in research, development and innovation in four main areas :
• defence and security,
• nuclear energy (fission and fusion),
• technological research for industry,
• fundamental research in the physical sciences and life sciences.

Drawing on its widely acknowledged expertise, and thanks to its 16000 technicians, engineers, researchers and staff, the CEA actively participates in collaborative projects with a large number of academic and industrial partners.

The CEA is established in ten centers spread throughout France
  

Reference

SL-DRF-24-0362  

Direction

DRF

Thesis topic details

Category

Life Sciences

Thesis topics

Nano-object simulations in biological media

Contract

Thèse

Job description

Understanding the non-specific or specific interactions between biomolecules and nanomaterials is key to the development of safe nanomedicines and nanoparticles. Indeed, adsorption of biomolecules is the first process occurring after the introduction of biomaterials into the human body, which controls their biological response. In this thesis, we will simulate the interface between nanosystems and biomolecules on a scale of a hundred nanometers, using the new exascale computing resources available at the CEA from 2025 (Jules Verne machine installed at the CCRT).

University / doctoral school

Sciences Chimiques: Molécules, Matériaux, Instrumentation et Biosystèmes (2MIB)
Paris-Saclay

Thesis topic location

Site

Saclay

Requester

Position start date

01/09/2024

Person to be contacted by the applicant

BOULARD Yves yves.boulard@cea.fr
CEA
DRF/JOLIOT/I2BC/
CEA/SACLAY
DRF/JOLIOT/SB2SM
91191 Gif-sur-Yvette
France
+33 169083584

Tutor / Responsible thesis director

RENAULT Jean-Philippe jean-philippe.renault@cea.fr
CEA
DRF/IRAMIS/NIMBE/LIONS
IRAMIS/NIMBE/LIONS
CEA/Saclay
Bat. 546
91191 Gif/Yvette
01 69 08 15 50

En savoir plus

https://iramis.cea.fr/Phocea/Membres/Annuaire/index.php?uid=jrenault
https://iramis.cea.fr/nimbe/lions/