General information
Organisation
The French Alternative Energies and Atomic Energy Commission (CEA) is a key player in research, development and innovation in four main areas :
• defence and security,
• nuclear energy (fission and fusion),
• technological research for industry,
• fundamental research in the physical sciences and life sciences.
Drawing on its widely acknowledged expertise, and thanks to its 16000 technicians, engineers, researchers and staff, the CEA actively participates in collaborative projects with a large number of academic and industrial partners.
The CEA is established in ten centers spread throughout France
Reference
SL-DRF-25-0508
Direction
DRF
Thesis topic details
Category
Condensed Matter Physics, chemistry, nanosciences
Thesis topics
Very high energy electrons radiotherapy with beams from a wakefield accelerator
Contract
Thèse
Job description
Research objectives:
Use numerical modelling to optimize the properties of laser-plasma accelerators in the 50 MeV-200 MeV range for VHEE radiotherapy:
(i) optimize the properties of a laser-plasma accelerator (energy spread, divergence) with electron beams injected from a plasma-mirror injector using the WarpX and HiPACE++ codes.
(ii) Study the impact of such electron beams on DNA using Geant4DNA.
This numerical modelling will then be used to guide/design/interpret experiments of radiobiology on in-vitro biological samples that are planned at our in-house 100 TW laser facility at CEA during the project. This will be carried out in the context of research project FemtoDose funded by the French National Research Agency.
The researcher will benefit from a large variety of training available at CEA on HPC and computer programming as well as training at our industrial partners (ARM, Eviden) and Université Paris Saclay, which has MSc courses in radiobiology and also hosts a research centre (INanoTherad) dedicated to novel radiotherapy treatments, gathering physicists, radiobiologists and medical doctors. The activities will be carried out in the framework of the Marie Sklodowska Curie Action Doctoral Network EPACE (European compact accelerators, their applications, and entrepreneurship)
University / doctoral school
Ondes et Matière (EDOM)
Paris-Saclay
Thesis topic location
Site
Saclay
Requester
Position start date
01/05/2025
Person to be contacted by the applicant
DOBOSZ DUFRÉNOY Sandrine
sandrine.dobosz@cea.fr
CEA
DRF/IRAMIS/LIDyL
Groupe Physique à Haute Intensité
DSM/IRAMIS/LIDYL/PHI
Laboratoire Interactions, Dynamique et Lasers
CEA Saclay, Bât 701 p 50
91 191 Gif-sur-Yvette Cedex
01.69.08.63.40
Tutor / Responsible thesis director
VINCENTI Henri
henri.vincenti@cea.fr
CEA
DRF/IRAMIS/LIDyL/PHI
CEA Saclay, 91191 Gif-Sur-Yvette, FRANCE
0169080376
En savoir plus
https://iramis.cea.fr/lidyl/phi/pisp/sandrine-dobosz-dufrenoy-2/
https://iramis.cea.fr/lidyl/phi/
https://iramis.cea.fr/lidyl/phi/pisp/henri-vincenti-2/