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Design of plasmonic nanocomposite membranes for biomolecule detection


Thesis topic details

General information

Organisation

The French Alternative Energies and Atomic Energy Commission (CEA) is a key player in research, development and innovation in four main areas :
• defence and security,
• nuclear energy (fission and fusion),
• technological research for industry,
• fundamental research in the physical sciences and life sciences.

Drawing on its widely acknowledged expertise, and thanks to its 16000 technicians, engineers, researchers and staff, the CEA actively participates in collaborative projects with a large number of academic and industrial partners.

The CEA is established in ten centers spread throughout France
  

Reference

SL-DRF-25-0352  

Direction

DRF

Thesis topic details

Category

Condensed Matter Physics, chemistry, nanosciences

Thesis topics

Design of plasmonic nanocomposite membranes for biomolecule detection

Contract

Thèse

Job description

Detection of specific small biomolecules amounts is usually challenging. Recently, nanomaterials have provided new materials with interesting optical properties for such an application, especially plasmonic nanomaterials.

In this project, we propose the design of a specific type of nanocomposite made from the incorporation of plasmonic nanoparticles (NPs) within track-etched functionalized polymer membranes. The tuning of the material plasmonic response will be achieved by a controlled in situ NP synthesis directly within the membrane nanopores, through chemical and physico-chemical processes. Especially, the use of radiation (electron beam, ?-rays) to induce the in situ reduction of the metallic precursor will be studied. Ionizing beams (Swift Heavy ions) will also serve to structure the polymer matrix in nanoporous membrane with controlled nanoporosity. The relation between the composite nanostructure and its optical properties will be thoroughly investigated in order to determine the ideal material for biomolecule detection, which will be tested on model molecules such as proteins or virus-like particles (VLPs) in the final part of the project.

University / doctoral school

Ecole Doctorale de l’Institut Polytechnique de Paris (IP Paris)
Ecole Polytechnique

Thesis topic location

Site

Saclay

Requester

Position start date

01/10/2025

Person to be contacted by the applicant

AUBRIT Florian florian.aubrit@polytechnique.edu
CEA
DRF/IRAMIS/LSI/LSI
Laboratoire des Solides Irradiés (LSI)
École polytechnique
Route de Saclay
91120 Palaiseau
France
+33169334544

Tutor / Responsible thesis director

CLOCHARD Marie-Claude marie-claude.clochard@polytechnique.edu
CEA
DRF/IRAMIS/LSI/LSI
LSI Ecole Polytechnique 91128 Palaiseau
0169334526

En savoir plus

https://iramis.cea.fr/annuaire/?uidc=MzAzNExLSkoGAA
https://portail.polytechnique.edu/lsi/en