The aim of this PhD thesis is to develop new clinical assessment methods using surface haptics technologies, developed at CEA List, and machine learning algorithms for testing and monitoring tactile-motor integration. In particular, the thesis will investigate and validate the development of a multimodal analytics pipeline that converts surface haptics signals and dexterity exercises inputs (i.e. tactile stimulation events, finger kinematics, contact forces, and millisecond timing) into reliable, interpretable biomarkers of tactile perception and sensorimotor coupling, and then classify normative versus atypical integration patterns with clinical fidelity for assessment.
Expected results: a novel technology and models for the rapid and feasible measurement of tactile-motor deficits in clinical setting, with an initial validation in different neurodevelopmental disorders (i.e. first-episode psychosis, autism spectrum disorder, and dyspraxia). The methods developed and data collected will provide:
(1) an open, versioned feature library for tactile–motor assessment;
(2) classifiers with predefined operating points (sensitivity/specificity);
(3) and an on-device/edge-ready pipeline, i.e. able to run locally on a typical tablet hardware whilst meeting constraints on latency, computing, and data privacy. Success will be measured by reproducibility of features, clinically meaningful effect sizes, and interpretable decision logic that maps back to known neurophysiology rather than artefacts.